How many times a day can I use Sinus Rinse? Can I use it more often while having a head cold with a lot of nasal drainage? Posted on: January 1, 2019 0 Vote Up Vote Down Ask A Doctor Staff asked 5 years ago How many times a day can I use Sinus Rinse? Can I use it more often while having a head cold with a lot of nasal drainage? 1 Answers 0 Vote Up Vote Down Ask A Doctor Staff answered 5 years ago Rinse twice a day for maximum relief. You can rinse more than twice a day, but it may not provide any additional benefit. Please follow the advice of your physician. Please login or Register to submit your answer Username or Email Address Password Remember Me